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matthew callaghan

Headline: Inventor
Groups: Social e-challenge Competition 2009 [inactive], [OLD] Social e-challenge Competition 2008 [INACTIVE]
Interested in: Consulting opportunities, Meeting new people, Patenting my idea, Professional opportunities, Receiving feedback

WORK EXPERIENCE

Employer: Medscape, Inc., New York, NY
Position: Producer
Time period: January 2000 - June 2000
Description: Interactive content,
Design and production - online medical journal (www.medscape.com)

Employer: The Wistar Institute, Philadelphia, PA
Position: Research Assistant/Programmer
Time period: October 1998 - December 1999
Description: Department of Bioinformatics, Michael Showe, PhD

Employer: Genentech, Inc., South San Francisco, CA
Position: Programmer/Software Designer
Time period: October 1997 - October 1998
Description: Department of Operations

Employer: Stanford University Department of Plastic Surgery
Position: Post-doctoral Fellow
Time period: December 2005
Description: Plastic Surgery Research Laboratory, Dr. Geoffrey C. Gurtner
Focus: NIH-funded research on diabetic vascular complications and progenitor cell function

Employer: New York University Department of Plastic Surgery
Position: Research Fellow
Time period: December 2003
Description: Laboratory of Microvascular Research and Tissue Engineering, Dr. Geoffrey C. Gurtner
Full-year stipend awarded by the SUNY Downstate Alumni Association

Employer: Alpha Omega Alpha Research Fellowship
Position: Research Fellow
Time period: December 2003
Description: “Vasculogenesis in response to hypoxia through the recruitment and
proliferation of circulating endothelial precursor cells”
New York University School of Medicine, Department of Plastic Surgery

Employer: SUNY Downstate Research Fellowship
Position: Research Fellow
Time period: December 2001
Description: “Applications for recombinant VEGF in diabetic wound healing”
New York University School of Medicine, Department of Plastic Surgery

Employer: Oxo, Inc. Student Fellowship
Position: Research Fellow
Time period: December 1996
Description: Focus: Product design for the elderly and handicapped

PUBLICATIONS

Articles: Callaghan MJ, Hamou C, Thangarajah H, Chang E, Grogan RH, Gurtner GC. Role of mesenchymal stem cells in
ischemic neovascularization. Accepted, Plastic and Reconstructive Surgery, 2007.
Callaghan MJ, Chang E, Seiser N, Aarabi S, Ghali S, Kinnucan ER, Michaels J, Heitman DJ, Gurtner GC.
Accelerated wound healing in pulsed electromagnetic fields. Accepted, Plastic and Reconstructive Surgery, 2007.
Callaghan MJ, Longaker MT, Gurtner GC. Progress and potential for regenerative medicine.
Annual Review of Medicine, March, 2007.
Capla JM, Callaghan MJ, Grogan R, Galiano RD, Tepper OM, Ceradini DJ, Gurtner GC. Endothelial progenitor
cells from type-II diabetics exhibit impaired adhesion, migration and proliferation in response to hypoxia. Plastic and
Reconstructive Surgery, January 2007.
Gold LI, Rahman M, Blechman KM, Greives MR, Churgin S, Michaels J, Callaghan MJ, Cardwell NL,
Pollins AC, Michalak M, Siebert JW, Levine JP, Gurtner GC, Nanney LB, Galiano RD, Cadacio CL.
Overview of the role for calreticulin in the enhancement of wound healing through multiple biological
effects. J Invest Dermatol, September 2006.
Capla JM, Ceradini DJ, Tepper OM, Callaghan MJ, Bhatt KA, Galiano RD, Levine JP, Gurtner GC.
Skin graft vascularization involves precisely regulated regression and replacement of endothelial cells
through both angiogenesis and vasculogenesis. Plastic and Reconstructive Surgery. March 2006.
Callaghan MJ, Ceradini DJ, Gurtner GC. The impact of diabetes on endothelial progenitor cell function and
ischemic vascular complications. Antioxidants and Redox Signaling, November 2005.
Tepper O, Capla J, Galiano RD, Ceradini D, Callaghan MJ, Bhatt KA, Kleinman M, Gurtner GC.
Postnatal vasculogenesis by bone marrow-derived progenitor cells in situ. Blood, February 2005.
Callaghan MJ, Tepper OM, Chang E, Galiano RD, Bhatt KA, Bahastrani S, Simon BJ, Gan J, Hopper RA,
Levine JP, Gurtner GC. Electromagnetic fields increase in vitro and in vivo angiogenesis through endothelial
release of FGF-2. The FASEB Journal, August 2004.
Ceradini DJ, Kulkarni A, Callaghan MJ, Tepper OM, Bastidas N, Galiano RD, Kleinman ME, Bhatt KA,
Levine JP, Gurtner GC. Stem/progenitor cell trafficking is regulated by hypoxic gradients through HIF-1
induction of SDF-1. Nature Medicine, August 2004.
Galiano RD, Tepper O, Pelo C, Bhatt K, Callaghan MJ, Bastidas N, Bunting S, Steinmetz HG,
Gurtner GC. Topical VEGF accelerates diabetic wound healing through increased angiogenesis and by
mobilizing and recruiting bone marrow derived cells. American Journal of Pathology, June 2004.
Bhatt KA, Araabi S, Bastidas N, Greives M, Ghali S, Tabball G, Thibonnier A, Callaghan MJ, Ceradini DJ,
Holmes JW, Yee H, Gurtner GC. Mechanical strain induces hypertrophic scarring by decreasing akt-dependent
apoptosis. Under review, American Journal of Pathology, 2007.
Callaghan MJ, Grogan RH, Ingraham CR, Capell BC, Pelo CR, Gurtner GC. Diabetes potentiates p53-mediated
apoptosis after ischemic injury. Under review, Plastic and Reconstructive Surgery, 2007.
Ceradini DJ, Hoffman S, Callaghan MJ, Edelstein D, Brownlee M, Gurtner GC. Therapeutic blockade of
reactive oxygen species prevents post-ischemic vascular complications of diabetes. In submission, 2007.
DiGioia AM, Simon DA, Jaramaz B, Blackwell M,Morgan F, O'Toole RV, Colgan B, Callaghan MJ,
Kischell I. HipNav: Pre-operative Planning and Intra-operative Navigational Guidance for Acetabular Implant
Placement in Total Hip Replacement Surgery. Carnegie Mellon Robotics Institute, Medical Robotics and
Computer Assisted Surgery 1997.
Papers: Patents:
Pneumatic pressure-cycled spontaneous assist ventilator, file # US60/852110
Pulsed electromagnetic field delivery for diabetic wound healing, filed 2007

INFORMATION

Hobbies: Alto saxophone, drawing, vintage sportscars and motorcycles
Memberships: California Medical Society
American College of Surgeons
American Medical Association
American College of Physicians
Founder: The Downstate Investment Group
Founder: Operation Smile, Downstate Chapter
Vice president: SUNY Downstate Surgery Club
Awards: American Medical Association Seed Grant - 2005
“Tumor Angiogenesis in Electromagnetic Fields”
New York University Medical Center, Department of Plastic Surgery
First Place: Plastic Surgery Education Foundation Scientific Essay Contest, 2004. Postnatal
vasculogenesis by bone marrow-derived progenitor cells in situ. Tepper OM, Callaghan MJ,
Capla JM, Galiano RD, Ceradini DJ, Gurtner GC.
Peter J. Gingrass, MD Memorial Award, Plastic Surgery Research Council, 2004. Human endothelial
progenitor cells from type-II diabetics exhibit impaired adhesion, migration and proliferation in response
to hypoxia. Capla JM, Callaghan MJ, Galiano RD, Tepper OM, Ceradini DJ, Gurtner GC.
First Place: ASIM/ACP Annual Research Competition, 2003. Topical VEGF treatment of diabetic
cutaneous wounds. Callaghan MJ, Tepper OM, Galiano RD, Levine JP, Gurtner GC.

matthew's Startups (1)

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  • Aer

    Mission: Eliminate unnecessary deaths associated with respiratory illnesses in developing nations by providing low cost mechanical ventilation.

matthew's Contacts (1)

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  • Felix Mathew

    Indian, 21, Vice President, BASES Entrepreneur's Challenge, Co-lead, 8th Start-Up@Singapore, Singapore's premier business plan competition. Computer Science Major, Addicted to startups and soccer